Dna Fish Is Used For
In oncological patients, FISH method is used to detect or confirm aberrations that cannot be identified by standard karyotyping. The FISH method is generally quite sensitive and it is also commonly used to monitor the treatment of patients with onco-hematological diseases. In non-oncological patients such prenatal diagnostics, FISH analysis complements and in certain cases replaces cytogenetic analysis of peripheral blood, amniotic fluid, and chorionic villus samples. FISH is used to confirm the cytogenetic findings and also to detect various aberrations that cannot be detected by karyotyping due to its low sensitivity, e.g., microdeletion syndromes.