BioMolecular’ Ultra-Sensitive Mutation Detection Kits provide Clonal Differential Amplifier (CloDiA™) PCR using novel and proprietary primers to amplify somatic mutations and suppress or block the amplification of wild type gene in human genomic DNA.
CloDiA™ PCR includes two types of technique - Unindel™ PCR and Stuntmer™ PCR. Unindel™ PCR is designed to detect a broad range of insertions/deletions (universal insertions/deletions) in the target region. The three-primer set comprising forward primer, reverse primer and blocker inhibits amplification of wild type gene but enables amplification of exonic insertions/deletions.
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PCR KIT
Stuntmer™ PCR is designed
Stuntmer™ PCR is designed to detect a broad range of point mutations in the target region. Dual port primer of R Port and E Port is designed for self-competition to preferably amply mutated gene but suppress wild type gene amplification. This sensitive and specific method enables the detection of less than 1% (as little as 20 ng to 100 ng) of) mutant genes mixed with the wild type. Besides known mutations, this method can detect unknown mutations in the target region.
Products by Cancer Types
Products by Gene Types
| Cat. No. | Description | Size | Datasheet |
|---|---|---|---|
|
ABL0001-20 ABL0001-50 |
Ultra-Sensitive ABL Mutation Detection Kit | 20 tests 50 tests |
ABL0001 |
| AKT30001-20
AKT30001-50 |
Ultra-Sensitive AKT3 Mutation Detection Kit | 20 tests 50 tests |
AKT30001 |
| ASXL10001-20
ASXL10001-50 |
Ultra-Sensitive ASXL1 Mutation Detection Kit | 20 tests 50 tests |
ASXL10001 |
| BRAF0001-20
BRAF0001-50 |
Ultra-Sensitive BRAF Mutation Detection Kit | 20 tests 50 tests |
BRAF0001 |
| DNMT3A0001-20
DNMT3A0001-50 |
Ultra-Sensitive DNMT3A Mutation Detection Kit | 20 tests 50 tests |
DNMT3A0001 |
| CALR0001-20
CALR0001-50 |
Ultra-Sensitive Calreticulin (CALR) Mutation Detection Kit | 20 tests 50 tests |
CALR0001 |
| EGFR0001-20
EGFR0001-50 |
Ultra-Sensitive EGFR Mutation Detection Kit | 20 tests 50 tests |
EGFR0001 |
| FLT30001-20
FLT30001-50 |
Ultra-Sensitive FLT3 Mutation Detection Kit | 20 tests 50 tests |
FLT30001 |