FISH tests can detect certain types of genetic abnormalities that are too small to be detected by chromosome analysis, and the tests can be performed on non-dividing cells, which eliminates cell culture time and allows examination of cells that do not grow well in culture.
FISH testing can be used to diagnose certain congenital disorders, such as microdeletion syndromes, as well as genetic changes associated with some types of leukemia and cancer
FISH test can also provide additional information that helps predict a patient’s outcome and whether he or she is likely to respond to certain chemotherapy drugs, in cases where a type of cancer has already been diagnosed.
Abnormal cells can be visualized and counted using a fluorescence microscope. Abnormalities found in cancer cells include break apart and rearrangement (translocation, inversion), fusion, deletion, and amplification (duplication).

Our Fast FISH probes [FastProbe®] do not contain Repetitive Sequences resulting in:
High specificity: Do not bind to non-target fragments but only to target fragments.
High sensitivity: Effective detection of small fragments.
Strong fluorescent signal: Not obscured by background color and probe signal.
Fluorescent background and noise are low: Not easy to mask weak signals.